| Diana Ross |
Herself |
| Marie Osmond |
Herself |
| Johnny Mathis |
Himself |
| Quentin Tarantino |
Himself |
| Donny Osmond |
Himself |
| José Feliciano |
Himself |
| Billy Crystal |
Himself |
| Joey Scarbury |
Himself |
| John Schneider |
Himself |
| Wink Martindale |
Himself |
| Gary Portnoy |
Himself |
| Diahann Carroll |
Julia Baker - 'Gray Anatomy' Skit |
| Kate Walsh |
Herself |
| Danielle Spencer |
Herself |
| Adam West |
Himself |
| Jimmie Walker |
Himself |
| Burt Ward |
Himself |
| Anson Williams |
Himself |
| Carl Reiner |
Himself |
| Don Most |
Himself |
| James Burrows |
Himself |
| Justin Chambers |
Himself |
| Kelsey Grammer |
Himself |
| Larry Gelbart |
Himself |
| Larry Hagman |
Himself |
| Patrick Dempsey |
Himself |
| Peter Marshall |
Himself |
| Robert Guillaume |
Himself |
| Shonda Rhimes |
Herself |
| Steve Kanaly |
Himself |
| Tom Arnold |
Himself |
| Alison Arngrim |
Herself |
| Amy Linker |
Herself |
| Bebe Neuwirth |
Herself |
| Bernie Kopell |
Dr. Adam Bricker - 'Gray Anatomy' skit |
| BernNadette Stanis |
Herself |
| Betsy Beers |
Herself |
| Chad Everett |
Dr. Joe Gannon - 'Gray Anatomy' skit |
| Chandra Wilson |
Herself |
| Charlene Tilton |
Herself |
| Christopher Knight |
Himself |
| Ed Begley Jr. |
Dr. Victor Ehrlich - 'Gray Anatomy' skit |
| Eric Jacobson |
Himself (as Miss Piggy) |
| Glen Charles |
Himself |
| Hilary Swank |
Herself |
| Ja'net DuBois |
Herself |
| James Pickens Jr. |
Himself |
| Jane Seymour |
Dr. Michaela Quinn - 'Gray Anatomy' skit |
| Jeremy Piven |
|
| Joe Leahy |
Voice of TV Land |
| John Amos |
Himself |
| John Ratzenberger |
Himself |
| Johnny Brown |
Himself |
| Judy Kilch |
Herself - bartender |
| Julie Newmar |
|
| Ken Kercheval |
Himself |
| Kevin Alexander Stea |
Dancer |
| Les Charles |
Himself |
| Lew Rinker |
Himself - bartender |
| Linda Gray |
Herself |
| Loretta Swit |
Major Margaret Houlihan - 'Grey Anatomy' Skit |
| Marla Gibbs |
Herself |
| Mary Crosby |
Herself |
| Mary Tyler Moore |
Herself |
| Maureen McCormick |
Herself - 'Gray Anatomy' Skit |
| Megan Mullally |
Herself - Host |
| Monty Hall |
Himself |
| Neosha Morris |
Himself - mailman |
| Norman Lear |
Himself |
| Patrick Duffy |
Himself |
| Ralph Carter |
Himself |
| Rhea Perlman |
Herself |
| Richard Chamberlain |
Dr. Kildare - 'Gray Anatomy' skit |
| Robert Downey Jr. |
Himself |
| Shelley Long |
Herself |
| Sheree J. Wilson |
Herself |
| Sid Caesar |
Himself |
| Steve Whitmire |
Himself (as Kermit the Frog) |
| Susan Howard |
Herself |
| T.R. Knight |
Himself |
| Ted Danson |
Himself |
| Tichina Arnold |
Herself |
| Tina Yothers |
Herself |
| Tom Wopat |
Himself |
| Victoria Johnson |
Herself - Professor of Television |
| Zachary Woodlee |
Dancer |
